What is EarlyCDT®-Lung?
EarlyCDT®-Lung is a simple blood test which is ordered by a Doctor to aid in the risk assessment and early detection of lung cancer.
When a tumour is present, it produces abnormal proteins (known as antigens). Cancer antigens are different to normal antigens so the body reacts to these antigens by producing autoantibodies. These autoantobodies, which can rise in the earliest stages of cancer and have been shown to be present at all stages, are produced in sufficient quantities to be measured in an individual's blood using a simple blood test, EarlyCDT-Lung. The EarlyCDT-Lung test measures a panel of seven autoantibodies to detect the presence of lung cancer.
EarlyCDT-Lung has been developed so that individuals at moderate or high risk of developing lung cancer can benefit from an increased chance that lung cancer can be detected at the earliest possible stages, when treatment can be most successful.
EarlyCDT-Lung offers a complementary approach to annual CT screening, seen as the gold standard in the USA for early lung cancer detection. As a simple blood test, EarlyCDT-Lung can be used when individuals are unwilling or unable to undergo lifelong, annual CT screening. It can also be used when an individual is at increased risk but does not meet the criteria for annual CT screening. In either case, a positive EarlyCDT-Lung result can be followed by suitable CTs at appropriate intervals in order to detect a lung cancer early, with the patient, physician and insurers better aware of the risk of cancer developing.
The EarlyCDT-Lung test can also be used in conjunction with diagnostic imaging techniques to further assess the risk of lung cancer being present where indeterminate lung nodules have been detected but have not been diagnosed as malignant.
This is not a genetic test for predisposition - a positive test may indicate the presence of the malignant disease. The test is sent to and performed in Oncimmune's CLIA-certified laboratory in the Kansas City area, USA. Currently, EarlyCDT-Lung is in use by more than 2,000 physicians across the United States and more than 125,000 tests have already been performed. The test has aided in the detection of numerous early stage lung cancers. It is now also available in the UK and other regions.